![]() Lactate normalization may be delayed to after shock resolution.Hyperlactatemia may be caused by factors other than tissue hypoperfusion (ie liver or kidney failure, metabolic changes or drugs).However problems exist with lactate as a target, including: The surviving sepsis campaign recommends targeting the normalization of lactate when resuscitating patients with septic shock. ![]() ![]() In adult patients with early septic shock, does peripheral perfusion-targeted resuscitation, compared to lactate level-targeted resuscitation, improve all cause mortality at 28 days?.Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock
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